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r-Retinoate Day & Night

Medik8 r-Retinoate Day & Night 50ml

%0 4.65 | 107 reviews
Box

£149.00 (£2.98 per ml)

In stock

If you like we can let you know when we have some more.

r-Retinoate Day & Night is Medik8’s most remarkable vitamin that can be used both day and night for faster, visible brightening and smoothing results

Powered by Medik8’s exclusive encapsulated retinyl retinoate, which has been clinically proven to be 8x more powerful than standard retinol* in delivering visible age-defying results.

This luxurious multi-step, all-in-one serum combines retinyl retinoate with hyaluronic acid and stabilised vitamin C for maximum visible improvement in the skin’s texture, tone and radiance.

Combining groundbreaking science with an uplifting sensorial experience, r-Retinoate Day & Night is suitable for the most sensitive skin types.
*H. Kim et al., Synthesis and in vitro biological activity of retinyl retinoate, a novel hybrid retinoid derivative, Bioorganic & Medicinal Chemistry, 2008, 15;16(12), pp 6387-93

Key Benefits:
Accelerated Age-Defying Results, Day & Night
Uniquely photostable, retinyl retinoate doesn't lose its power in sunlight. Therefore, it delivers visible smoothing, illuminating & revitalising benefits both morning & night.

8x Stronger Than Retinol
Medik8-exclusive encapsulated retinyl retinoate is proven to be gentle yet 8x more powerful than standard retinol* in delivering visible age-defying results.
*H. Kim et al., Synthesis and in vitro biological activity of retinyl retinoate, a novel hybrid retinoid derivative, Bioorganic & Medicinal Chemistry, 2008, 15;16(12), pp 6387-93

3-in-1 Time-Saver
Delivers all the visible wrinkle-smoothing, hydrating & brightening benefits of vitamin A, vitamin C and hyaluronic acid in one sublime formula.

Key Ingredients:
Encapsulated Retinyl Retinoate
Exclusive to Medik8, this unique and patented vitamin A molecule is the breakthrough result of 8 years of expert research. Retinyl retinoate is proven to be 8x more powerful than classic retinol* in delivering astonishing age-defying results.
*H. Kim et al., Synthesis and in vitro biological activity of retinyl retinoate, a novel hybrid retinoid derivative, Bioorganic & Medicinal Chemistry, 2008, 15;16(12), pp 6387-93

3% Stabilised Vitamin C (tetrahexyldecyl ascorbate)
This stable, low-irritation form of vitamin C is incredibly effective on the skin; delivering exceptional protection against ageing free radicals. Supporting collagen production and brightening the skin tone, it leaves the complexion visibly more even, radiant and youthful-looking.

Hyaluronic Acid
An incredibly hydrating ingredient, hyaluronic acid attracts and retains more than 1,000 times its own weight in water and draws moisture in the upper layers of the skin; leaving it looking visibly supple and deeply hydrated.

Vitamin E
Rich in antioxidants, vitamin E helps to protect the skin against ageing free radicals. It also helps to boost the power of vitamin C for maximum visible results.

Good to Know:
NO ARTIFICIAL FRAGRANCE
NO SYNTHETIC COLOURS
PARABEN FREE
ALCOHOL FREE

Directions

Step 1
After cleansing in the evening, massage 2 pumps of r-Retinoate Day & Night evenly across face, neck and décolletage.

NOTE
You should always use a sunscreen the morning after using vitamin A.

How to Layer r-Retinoate Day & Night
AM: Cleanse, tone and apply r-Retinoate Day & Night. Always follow with sunscreen.
PM: Cleanse, tone and apply r-Retinoate Day & Night. Follow with your moisturiser.

More information

NO ARTIFICIAL FRAGRANCE
NO SYNTHETIC COLOURS
PARABEN FREE
ALCOHOL FREE

Ingredients

Aqua (Water), Caprylic/Capric Triglyceride, Glycerin, Butylene Glycol, Isododecane, Squalane, Cetearyl Alcohol, Dimethicone, Cetearyl Olivate, Sodium Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Polylactic Acid, Cyclodextrin, PPG-12/SMDI Copolymer, Sorbitan Olivate, Titanium Dioxide, Eclipta Prostrata Extract, Phenethyl Alcohol, Melia Azadirachta Leaf Extract, Phenoxyethanol, Cholesteryl Nonanoate, Sodium Hyaluronate, Tocopheryl Acetate, Rubus Chamaemorus (Cloudberry) Seed Oil, Canola Oil, Xanthan Gum, Pentylene Glycol, Retinal, Retinyl Retinoate, Citric Acid, Alumina, Isostearic Acid, Lecithin, Polyglyceryl-3 Polyricinoleate, Polyhydroxystearic Acid, Stearic Acid, Ceramide AP, Moringa Oleifera Seed Oil, Sodium Lauroyl Lactylate, Vanilla Planifolia (Vanilla) Fruit Extract, Ethylhexylglycerin, Linoleic Acid, Palmitic Acid, Ceramide NP, Daucus Carota Sativa (Carrot) Seed Oil, Disodium EDTA, Phytosterols, Lonicera Japonica (Honeysuckle) Flower Extract, 3-O-Ethyl Ascorbic Acid, Lonicera Caprifolium (Honeysuckle) Flower Extract, Sodium Polyaspartate, Phytosphingosine, Parfum*, Copper Palmitoyl Heptapeptide-14, Heptapeptide-15 Palmitate, Ceramide EOP, Cholesterol, C12-16 Alcohols, Caprylyl Glycol, Carbomer, Hydrogenated Lecithin, Glyceryl Caprylate, Lactic Acid/Glycolic Acid Copolymer, Polyvinyl Alcohol, Phenylpropanol, BHT, Limonene, Linalool, Citral. *natural extracts

This list of ingredients may be subject to change, please consult the packaging of the product purchased.

+Offer

FREE Clarifying Foam™ 150ml when you spend £80 on Medik8.*

Discover a visibly decongested, clearer and smoother-looking complexion that is less prone to breakouts with Medik8’s Clarifying Foam.

 

*One free gift per order. Valid until the 26th of January or whilst stock lasts. Your free gift will automatically add to the shopping bag page. Total at order summary must be £80 or more worth of Medik8 products, after any Promotion Code, Brands You Love discount and before delivery charges are applied. Cannot be used in conjunction with any other Promotion and this offer is not applicable to previously made or pending purchases. Excludes Gift Voucher, Sephora Favourites Advent Calendar and Fragrance Gift Box purchases. This offer is available online at Sephora.co.uk to UK Mainland customers only. 

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Rated 3 out of 5 by from Good product, bulky packaging This is nice product if you are prepared to pay the rather high price for convenience. But the packaging for 50ml is larger than many 100ml bottles, presumably to make it feel worth the money. What it means is lots of waste and filling space in a travel kit when it could be saving it by replacing multiple products.
Date published: 2026-01-03
Rated 5 out of 5 by from Fantastic all rounder cream Love this packaging, very easy regime to follow, love the results and the packaging is very pleasing
Date published: 2025-12-31
Rated 5 out of 5 by from Had been eyeing this up Had been eyeing this up for a while as a perfect way to up my morning skincare. This is perfect as you get multiple ingredients in one and it’s lightweight so sits under spf and/or makeup perfectly! The bottle looks sleek too which is an extra bonus.
Date published: 2025-12-29
Rated 5 out of 5 by from Review This is the second one I've bought. It's almost a one stop shop bar SPF - simple and effective. Skin feels hydrated and less crepey lines. Expensive but worth it.
Date published: 2025-12-26
Rated 5 out of 5 by from Retinoate® Day & Night Excellent Product Getting lots of compliments on my skin, even at my age of 74 in a few weeks time💖
Date published: 2025-09-11
Rated 5 out of 5 by from Great addition to my Medik8 routine This is really gentle in my sensitive skin but still really effective too. I use this in the morning and the fantastic all in one night time r-Retinoate at night. I then use this r-Retinoate Day/Night in the morning only. Loving the double effect of both r-Retinoate products. Individually they give great results but together they are the best combination
Date published: 2025-09-07
Rated 5 out of 5 by from Love this cream! Brilliant cream. Leaves my skin feeling soft and firm, it's such a lovely texture. Noticed a difference really quickly! The size of the bottle is quite big so it lasts for longer than you would expect. Will definitely buy again.
Date published: 2025-08-26
Rated 5 out of 5 by from Lovely product. Very easy to Lovely product. Very easy to apply and it seems to have an instant impact on the brightness of my skin
Date published: 2025-07-14
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