Medik8Exo-PDRN Prismatic+
Product Description
Boost skin's natural rejuvenation by +50%<1> with Exo-PDRN Prismatic+, a next-generation PDRN serum rooted in real skin biology. Designed to support the skin's key natural pathways, helping to restore visible vitality, refine tone and texture, boost luminosity and support calm, resilient-looking skin.
Central to the formula is our Rejuvenation Blueprint, built to address the 3 Rs of Rejuvenation: Recover, Restore and Recharge. This complete skin system delivers a multi-dimensional approach to visible vitality. 80
Prismatic PDRN helps provide essential building blocks to support and aid in optimal skin recovery and calm visible redness. A highly concentrated triple exosome complex, featuring up to 151 billion exosomes per bottle, and our breakthrough GF MiniProteinTM visibly restores by supporting skin's natural signalling processes that facilitate skin resilience and reinforce the skin barrier. An ATP Precursor helps recharge the skin's natural processes involved in visible rejuvenation, for a smoother, more revitalised complexion.
KEY BENEFITS
Visible Skin Rejuvenation
Scientifically proven to boost the skin's natural rejuvenation by over 50%.<1>
Restored Vitality & Luminosity
Clinically proven to improve the look of skin luminosity and vitality in 7 days.<2>
Refined Tone & Texture
Supports visibly smoother skin with improved tone and texture.
Visibly Calm, Resilient-Looking Skin
Clinically proven to improve skin barrier function in 7 days.<2>
Optimal Skin Recovery Support
Designed to support the skin's natural recovery processes, making it ideal for daily use and alongside professional treatments.
KEY INGREDIENTS
Prismatic PDRN
A pioneering form of vegan PDRN with a stable tetrahedral structure for optimal penetration. Composed of DNA particles that support skin recovery, help calm visible redness and reveal smoother, more youthful-looking skin.
Triple Exosome Complex
Designed to support natural skin signalling processes, resilience and recovery, helping to strengthen the skin barrier and promote a healthier, more radiant-looking complexion.
GF MiniProteinTM
Visibly improves the appearance of skin structure over time by helping to boost skin's collagen, elastin & hyaluronic acid levels.
ATP Precursor
An energy-carrying molecule that helps optimise the natural processes involved in visible skin rejuvenation.
HOW TO USE
After cleansing in the morning and evening, apply 1-2 pumps of Exo-PDRN Prismatic+ evenly across the face, neck & décolletage. Use light upward strokes and allow to fully absorb.
GOOD TO KNOW
CLINICALLY PROVEN
FRAGRANCE-FREE
DERMATOLOGICALLY TESTED
PROVEN GENTLE FORMULA
CERTIFIED BY THE VEGAN SOCIETY
7 days to improved skin barrier function<2>
7 days to improved skin luminosity<2>
7 days to visibly improved skin volume<2>
7 days to improved skin tone<2>
14 days to visibly improved wrinkles<2>
14 days to improved firmness<2>
100% agree this is the perfect post-procedure partner for their in-clinic PDRN treatment<3>
98% agree the results continue to get better with time<3>
<1> Proven via ex vivo study measuring Ki67 protein marker for cell proliferation vs. untreated control after 24 hours
<2> Proven via independent clinical study on Exo-PDRN Prismatic+ on 60 volunteers over 1 week
<3> Proven via independent consumer study conducted over 4 weeks on 52 participants who had received injectable polynucleotide treatments within a week of the study
Central to the formula is our Rejuvenation Blueprint, built to address the 3 Rs of Rejuvenation: Recover, Restore and Recharge. This complete skin system delivers a multi-dimensional approach to visible vitality. 80
Prismatic PDRN helps provide essential building blocks to support and aid in optimal skin recovery and calm visible redness. A highly concentrated triple exosome complex, featuring up to 151 billion exosomes per bottle, and our breakthrough GF MiniProteinTM visibly restores by supporting skin's natural signalling processes that facilitate skin resilience and reinforce the skin barrier. An ATP Precursor helps recharge the skin's natural processes involved in visible rejuvenation, for a smoother, more revitalised complexion.
KEY BENEFITS
Visible Skin Rejuvenation
Scientifically proven to boost the skin's natural rejuvenation by over 50%.<1>
Restored Vitality & Luminosity
Clinically proven to improve the look of skin luminosity and vitality in 7 days.<2>
Refined Tone & Texture
Supports visibly smoother skin with improved tone and texture.
Visibly Calm, Resilient-Looking Skin
Clinically proven to improve skin barrier function in 7 days.<2>
Optimal Skin Recovery Support
Designed to support the skin's natural recovery processes, making it ideal for daily use and alongside professional treatments.
KEY INGREDIENTS
Prismatic PDRN
A pioneering form of vegan PDRN with a stable tetrahedral structure for optimal penetration. Composed of DNA particles that support skin recovery, help calm visible redness and reveal smoother, more youthful-looking skin.
Triple Exosome Complex
Designed to support natural skin signalling processes, resilience and recovery, helping to strengthen the skin barrier and promote a healthier, more radiant-looking complexion.
GF MiniProteinTM
Visibly improves the appearance of skin structure over time by helping to boost skin's collagen, elastin & hyaluronic acid levels.
ATP Precursor
An energy-carrying molecule that helps optimise the natural processes involved in visible skin rejuvenation.
HOW TO USE
After cleansing in the morning and evening, apply 1-2 pumps of Exo-PDRN Prismatic+ evenly across the face, neck & décolletage. Use light upward strokes and allow to fully absorb.
GOOD TO KNOW
CLINICALLY PROVEN
FRAGRANCE-FREE
DERMATOLOGICALLY TESTED
PROVEN GENTLE FORMULA
CERTIFIED BY THE VEGAN SOCIETY
Directions
After cleansing in the morning and evening, apply 1-2 pumps of Exo-PDRN Prismatic+ evenly across the face, neck & décolletage. Use light upward strokes and allow to fully absorb.
Test results
+50% boost in natural skin rejuvenation<1>7 days to improved skin barrier function<2>
7 days to improved skin luminosity<2>
7 days to visibly improved skin volume<2>
7 days to improved skin tone<2>
14 days to visibly improved wrinkles<2>
14 days to improved firmness<2>
100% agree this is the perfect post-procedure partner for their in-clinic PDRN treatment<3>
98% agree the results continue to get better with time<3>
<1> Proven via ex vivo study measuring Ki67 protein marker for cell proliferation vs. untreated control after 24 hours
<2> Proven via independent clinical study on Exo-PDRN Prismatic+ on 60 volunteers over 1 week
<3> Proven via independent consumer study conducted over 4 weeks on 52 participants who had received injectable polynucleotide treatments within a week of the study
Ingredients
Aqua (Water), Glycerin, Niacinamide, Lactobacillus Ferment, Centella Asiatica Leaf Extract, Lactobacillus Extracellular Vesicles, DNA, Punica Granatum Extract, Laminaria Digitata Extract, Oligopeptide-1, Disodium Adenosine Triphosphate, Sodium Hyaluronate, Lysine HCl, Proline, Histidine HCl, Arginine, Threonine, Serine, Valine, Alanine, Panthenol, Glutamic Acid, Leucine, Glycine, Taurine, Allantoin, Isoleucine, Phenylalanine, Polyacrylate Crosspolymer-6, Magnesium Aspartate, Butylene Glycol, Citric Acid, Calcium Pantothenate, Ethylhexylglycerin, 1,2-Hexanediol, Pentylene Glycol, Benzyl Alcohol, Caprylyl Glycol, Dehydroacetic Acid, Phenoxyethanol, Sodium Citrate.
This list of ingredients may be subject to change, please consult the packaging of the product purchased.
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Rated 5 out of
5
by
Andrew S. from
Fab so far!!
[This review was collected as part of a promotion.] All feeling good so far as I am half way through the bottle. Has sat in nicely with my other products and I will definately buy another for a real long test of the product.
Works well with my moisturiser, no pilling or making my makeup patchy. Lovely!
Date published: 2026-08-25
Rated 3 out of
5
by
Sonia M. from
Exo-PDRN Prismatic+
[This review was collected as part of a promotion.] I have only used a sample of this product which isn’t enough time to comment
As I use other Medik 8 products for my skin type and they all make a big difference in how my skin looks
Date published: 2026-08-24
Rated 5 out of
5
by
Kathleen S. from
Fabulous product
[This review was collected as part of a promotion.] I cannot believe how lovely my skin feels after applying this product. My skin feels so hydrated and although I have only been using it for about 2 weeks I feel my complexion is looking so much better already.
Date published: 2026-08-24
Rated 5 out of
5
by
Ren B. from
Nice serum, good texture
[This review was collected as part of a promotion.] Lightweight gel texture, absorbed well before moisturiser but was a little sticky at first. Would need to use more to see results but I’m sure it’s just as effective as other serums. Would try full size from the sample.
Date published: 2026-08-23
Rated 5 out of
5
by
Sarah M. from
A powerful rejuvenation serum with real results
[This review was collected as part of a promotion.] I’m a beauty therapist specialising in skincare, and my entire routine now consists solely of Medik8 because the results genuinely outperform anything else I’ve used. Exo‑PDRN Prismatic+ has become one of my essential morning products. I’m very selective with what I invest in, and although I don’t usually spend this much on skincare, this serum earns its place in my routine because it delivers noticeable changes.
The formula is packed with advanced ingredients — prismatic PDRN for deep penetration, a highly concentrated triple exosome complex, and GF MiniProtein to support the skin’s natural repair and resilience. These aren’t marketing buzzwords; they translate into real improvements. My skin looks brighter, smoother, and more even, and I’ve seen a clear boost in vitality and firmness. The lightweight texture absorbs instantly and gives a fresh, healthy glow without any heaviness.
I don’t wear makeup and rely on semi‑permanent makeup, so achieving naturally radiant, healthy skin is my priority. This serum helps me maintain that “no‑makeup glow” every day. It’s one of the most effective rejuvenation products I’ve used, and it has become a staple I confidently recommend to clients who want visible results without needing cosmetic coverage.
Date published: 2026-08-23
Rated 5 out of
5
by
jennifer l. from
Easily and quickly absorbed and
Easily and quickly absorbed and gives a lovely base before serum. Used it twice daily for 4 weeks now and I do feel my skin texture and appearance is improving.
Date published: 2026-08-21
Rated 5 out of
5
by
Karen L. from
Exo PDRN Prismatic +
[This review was collected as part of a promotion.] I really love this product!
I was a bit wary as I have very dry skin , and thought it might be too drying and exaggerate my lines and wrinkles ? But no , absolutely not . I use it after cleansing in the morning and before my C Tetra luxe and it is a perfect combo.
My husband made a comment how fresh my skin was looking lately ? That’s a win win and I will definitely be buying again !
Date published: 2026-08-21
Rated 3 out of
5
by
Anna M. from
Not bad
[This review was collected as part of a promotion.] Hm, didn't get it at all, can't say it did anything. Layers well, but really can't say I have noticed anything change. Nice texture though, light.
Date published: 2026-08-21
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