Medik8Exo-PDRN Prismatic+
Boost skin's natural rejuvenation by +50%<1> with Exo-PDRN Prismatic+, a next-generation PDRN serum rooted in real skin biology. Designed to support the skin's key natural pathways, helping to restore visible vitality, refine tone and texture, boost luminosity and support calm, resilient-looking skin.
Central to the formula is our Rejuvenation Blueprint, built to address the 3 Rs of Rejuvenation: Recover, Restore and Recharge. This complete skin system delivers a multi-dimensional approach to visible vitality. 80
Prismatic PDRN helps provide essential building blocks to support and aid in optimal skin recovery and calm visible redness. A highly concentrated triple exosome complex, featuring up to 151 billion exosomes per bottle, and our breakthrough GF MiniProteinTM visibly restores by supporting skin's natural signalling processes that facilitate skin resilience and reinforce the skin barrier. An ATP Precursor helps recharge the skin's natural processes involved in visible rejuvenation, for a smoother, more revitalised complexion.
KEY BENEFITS
Visible Skin Rejuvenation
Scientifically proven to boost the skin's natural rejuvenation by over 50%.<1>
Restored Vitality & Luminosity
Clinically proven to improve the look of skin luminosity and vitality in 7 days.<2>
Refined Tone & Texture
Supports visibly smoother skin with improved tone and texture.
Visibly Calm, Resilient-Looking Skin
Clinically proven to improve skin barrier function in 7 days.<2>
Optimal Skin Recovery Support
Designed to support the skin's natural recovery processes, making it ideal for daily use and alongside professional treatments.
KEY INGREDIENTS
Prismatic PDRN
A pioneering form of vegan PDRN with a stable tetrahedral structure for optimal penetration. Composed of DNA particles that support skin recovery, help calm visible redness and reveal smoother, more youthful-looking skin.
Triple Exosome Complex
Designed to support natural skin signalling processes, resilience and recovery, helping to strengthen the skin barrier and promote a healthier, more radiant-looking complexion.
GF MiniProteinTM
Visibly improves the appearance of skin structure over time by helping to boost skin's collagen, elastin & hyaluronic acid levels.
ATP Precursor
An energy-carrying molecule that helps optimise the natural processes involved in visible skin rejuvenation.
HOW TO USE
After cleansing in the morning and evening, apply 1-2 pumps of Exo-PDRN Prismatic+ evenly across the face, neck & décolletage. Use light upward strokes and allow to fully absorb.
GOOD TO KNOW
CLINICALLY PROVEN
FRAGRANCE-FREE
DERMATOLOGICALLY TESTED
PROVEN GENTLE FORMULA
CERTIFIED BY THE VEGAN SOCIETY
7 days to improved skin barrier function<2>
7 days to improved skin luminosity<2>
7 days to visibly improved skin volume<2>
7 days to improved skin tone<2>
14 days to visibly improved wrinkles<2>
14 days to improved firmness<2>
100% agree this is the perfect post-procedure partner for their in-clinic PDRN treatment<3>
98% agree the results continue to get better with time<3>
<1> Proven via ex vivo study measuring Ki67 protein marker for cell proliferation vs. untreated control after 24 hours
<2> Proven via independent clinical study on Exo-PDRN Prismatic+ on 60 volunteers over 1 week
<3> Proven via independent consumer study conducted over 4 weeks on 52 participants who had received injectable polynucleotide treatments within a week of the study
Central to the formula is our Rejuvenation Blueprint, built to address the 3 Rs of Rejuvenation: Recover, Restore and Recharge. This complete skin system delivers a multi-dimensional approach to visible vitality. 80
Prismatic PDRN helps provide essential building blocks to support and aid in optimal skin recovery and calm visible redness. A highly concentrated triple exosome complex, featuring up to 151 billion exosomes per bottle, and our breakthrough GF MiniProteinTM visibly restores by supporting skin's natural signalling processes that facilitate skin resilience and reinforce the skin barrier. An ATP Precursor helps recharge the skin's natural processes involved in visible rejuvenation, for a smoother, more revitalised complexion.
KEY BENEFITS
Visible Skin Rejuvenation
Scientifically proven to boost the skin's natural rejuvenation by over 50%.<1>
Restored Vitality & Luminosity
Clinically proven to improve the look of skin luminosity and vitality in 7 days.<2>
Refined Tone & Texture
Supports visibly smoother skin with improved tone and texture.
Visibly Calm, Resilient-Looking Skin
Clinically proven to improve skin barrier function in 7 days.<2>
Optimal Skin Recovery Support
Designed to support the skin's natural recovery processes, making it ideal for daily use and alongside professional treatments.
KEY INGREDIENTS
Prismatic PDRN
A pioneering form of vegan PDRN with a stable tetrahedral structure for optimal penetration. Composed of DNA particles that support skin recovery, help calm visible redness and reveal smoother, more youthful-looking skin.
Triple Exosome Complex
Designed to support natural skin signalling processes, resilience and recovery, helping to strengthen the skin barrier and promote a healthier, more radiant-looking complexion.
GF MiniProteinTM
Visibly improves the appearance of skin structure over time by helping to boost skin's collagen, elastin & hyaluronic acid levels.
ATP Precursor
An energy-carrying molecule that helps optimise the natural processes involved in visible skin rejuvenation.
HOW TO USE
After cleansing in the morning and evening, apply 1-2 pumps of Exo-PDRN Prismatic+ evenly across the face, neck & décolletage. Use light upward strokes and allow to fully absorb.
GOOD TO KNOW
CLINICALLY PROVEN
FRAGRANCE-FREE
DERMATOLOGICALLY TESTED
PROVEN GENTLE FORMULA
CERTIFIED BY THE VEGAN SOCIETY
Directions
After cleansing in the morning and evening, apply 1-2 pumps of Exo-PDRN Prismatic+ evenly across the face, neck & décolletage. Use light upward strokes and allow to fully absorb.
Test results
+50% boost in natural skin rejuvenation<1>7 days to improved skin barrier function<2>
7 days to improved skin luminosity<2>
7 days to visibly improved skin volume<2>
7 days to improved skin tone<2>
14 days to visibly improved wrinkles<2>
14 days to improved firmness<2>
100% agree this is the perfect post-procedure partner for their in-clinic PDRN treatment<3>
98% agree the results continue to get better with time<3>
<1> Proven via ex vivo study measuring Ki67 protein marker for cell proliferation vs. untreated control after 24 hours
<2> Proven via independent clinical study on Exo-PDRN Prismatic+ on 60 volunteers over 1 week
<3> Proven via independent consumer study conducted over 4 weeks on 52 participants who had received injectable polynucleotide treatments within a week of the study
Ingredients
Aqua (Water), Glycerin, Niacinamide, Lactobacillus Ferment, Centella Asiatica Leaf Extract, Lactobacillus Extracellular Vesicles, DNA, Punica Granatum Extract, Laminaria Digitata Extract, Oligopeptide-1, Disodium Adenosine Triphosphate, Sodium Hyaluronate, Lysine HCl, Proline, Histidine HCl, Arginine, Threonine, Serine, Valine, Alanine, Panthenol, Glutamic Acid, Leucine, Glycine, Taurine, Allantoin, Isoleucine, Phenylalanine, Polyacrylate Crosspolymer-6, Magnesium Aspartate, Butylene Glycol, Citric Acid, Calcium Pantothenate, Ethylhexylglycerin, 1,2-Hexanediol, Pentylene Glycol, Benzyl Alcohol, Caprylyl Glycol, Dehydroacetic Acid, Phenoxyethanol, Sodium Citrate.
This list of ingredients may be subject to change, please consult the packaging of the product purchased.
Free Gift
FREE Total Moisture Daily Facial Cream 12.5ml, when you spend £70 on Medik8.*
Experience deeply hydrated and instantly plumped skin with Medik8’s multi-action, fragrance-free daily moisturiser.
*One free gift per order. Valid until the 3rd August or whilst stock lasts. Your free gift will automatically add to the shopping bag page. Total at order summary must be £70 or more worth of Medik8 products, after any Promotion Code, Brands You Love discount and before delivery charges are applied. Cannot be used in conjunction with any other Promotion and this offer is not applicable to previously made or pending purchases.
Excludes Gift Voucher, Sephora Favourites Advent Calendar and Fragrance Gift Box purchases. This offer is available online at Sephora.co.uk to UK Mainland customers only.
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Rated 5 out of
5
by
Thomas O. from
Definitely see a great improvement
[This review was collected as part of a promotion.] Definitely see a great improvement in my skin tone and will buy again
Date published: 2026-07-10
Rated 1 out of
5
by
Anonymous from
I have no idea how
[This review was collected as part of a promotion.] I have no idea how this is supposed to fit in with the liquid peptides advanced mp. Also have crystal retinal 10 and the rest of the expensive creams! Both say use am and pm! Which order is this supposed to be!
I’m totally confused and upset that I have spent a lot of money for me with absolutely no results. Very sad.
Date published: 2026-07-10
Rated 5 out of
5
by
Sally G. from
She was right to recommend
[This review was collected as part of a promotion.] My aesthetic practitioner recommended this product and I’m thrilled with the results already, I have noticed a difference in my skin texture and it has definitely reduced the lines on my cheek and improved my jaw line too.
Date published: 2026-07-09
Rated 5 out of
5
by
Yan C. from
The Ultimate Remedy for Tired, Aging Skin
[This review was collected as part of a promotion.] I bought this serum specifically to tackle the signs of aging and a complexion that was starting to look increasingly tired. I've been using it consistently morning and night for just under three weeks, and the biggest, most noticeable change is the overall radiance—my skin simply doesn't feel dull anymore.
It has an incredibly lightweight, silky fluid texture that sinks in instantly. It gives the skin an immediate, healthy-looking bounce and a fresh clarity that has completely woken up my complexion.
Date published: 2026-07-09
Rated 5 out of
5
by
Agnieszka P. from
Really hydrating
[This review was collected as part of a promotion.] My skin does feel and look much more hydrated! Overall feels firmer and healthier which is amazing considering I work night shifts and don’t get enough continuous sleep
Date published: 2026-07-08
Rated 5 out of
5
by
Judith K. from
Fabulous product skin felt and
[This review was collected as part of a promotion.] Fabulous product skin felt and looked good.
There are so many products now, it is difficult to choose.
Date published: 2026-07-08
Rated 5 out of
5
by
Cathy L. from
Really good product
[This review was collected as part of a promotion.] First time purchasing this product. . really good product so far.
Date published: 2026-07-08
Rated 5 out of
5
by
Miss R. from
First impression - I love
[This review was collected as part of a promotion.] First impression - I love this, super hydrating and compliments the rest of the medik8 skincare superbly.
Date published: 2026-07-08
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