Medik8Exo-PDRN Prismatic+
Boost skin's natural rejuvenation by +50%<1> with Exo-PDRN Prismatic+, a next-generation PDRN serum rooted in real skin biology. Designed to support the skin's key natural pathways, helping to restore visible vitality, refine tone and texture, boost luminosity and support calm, resilient-looking skin.
Central to the formula is our Rejuvenation Blueprint, built to address the 3 Rs of Rejuvenation: Recover, Restore and Recharge. This complete skin system delivers a multi-dimensional approach to visible vitality. 80
Prismatic PDRN helps provide essential building blocks to support and aid in optimal skin recovery and calm visible redness. A highly concentrated triple exosome complex, featuring up to 151 billion exosomes per bottle, and our breakthrough GF MiniProteinTM visibly restores by supporting skin's natural signalling processes that facilitate skin resilience and reinforce the skin barrier. An ATP Precursor helps recharge the skin's natural processes involved in visible rejuvenation, for a smoother, more revitalised complexion.
KEY BENEFITS
Visible Skin Rejuvenation
Scientifically proven to boost the skin's natural rejuvenation by over 50%.<1>
Restored Vitality & Luminosity
Clinically proven to improve the look of skin luminosity and vitality in 7 days.<2>
Refined Tone & Texture
Supports visibly smoother skin with improved tone and texture.
Visibly Calm, Resilient-Looking Skin
Clinically proven to improve skin barrier function in 7 days.<2>
Optimal Skin Recovery Support
Designed to support the skin's natural recovery processes, making it ideal for daily use and alongside professional treatments.
KEY INGREDIENTS
Prismatic PDRN
A pioneering form of vegan PDRN with a stable tetrahedral structure for optimal penetration. Composed of DNA particles that support skin recovery, help calm visible redness and reveal smoother, more youthful-looking skin.
Triple Exosome Complex
Designed to support natural skin signalling processes, resilience and recovery, helping to strengthen the skin barrier and promote a healthier, more radiant-looking complexion.
GF MiniProteinTM
Visibly improves the appearance of skin structure over time by helping to boost skin's collagen, elastin & hyaluronic acid levels.
ATP Precursor
An energy-carrying molecule that helps optimise the natural processes involved in visible skin rejuvenation.
HOW TO USE
After cleansing in the morning and evening, apply 1-2 pumps of Exo-PDRN Prismatic+ evenly across the face, neck & décolletage. Use light upward strokes and allow to fully absorb.
GOOD TO KNOW
CLINICALLY PROVEN
FRAGRANCE-FREE
DERMATOLOGICALLY TESTED
PROVEN GENTLE FORMULA
CERTIFIED BY THE VEGAN SOCIETY
7 days to improved skin barrier function<2>
7 days to improved skin luminosity<2>
7 days to visibly improved skin volume<2>
7 days to improved skin tone<2>
14 days to visibly improved wrinkles<2>
14 days to improved firmness<2>
100% agree this is the perfect post-procedure partner for their in-clinic PDRN treatment<3>
98% agree the results continue to get better with time<3>
<1> Proven via ex vivo study measuring Ki67 protein marker for cell proliferation vs. untreated control after 24 hours
<2> Proven via independent clinical study on Exo-PDRN Prismatic+ on 60 volunteers over 1 week
<3> Proven via independent consumer study conducted over 4 weeks on 52 participants who had received injectable polynucleotide treatments within a week of the study
Central to the formula is our Rejuvenation Blueprint, built to address the 3 Rs of Rejuvenation: Recover, Restore and Recharge. This complete skin system delivers a multi-dimensional approach to visible vitality. 80
Prismatic PDRN helps provide essential building blocks to support and aid in optimal skin recovery and calm visible redness. A highly concentrated triple exosome complex, featuring up to 151 billion exosomes per bottle, and our breakthrough GF MiniProteinTM visibly restores by supporting skin's natural signalling processes that facilitate skin resilience and reinforce the skin barrier. An ATP Precursor helps recharge the skin's natural processes involved in visible rejuvenation, for a smoother, more revitalised complexion.
KEY BENEFITS
Visible Skin Rejuvenation
Scientifically proven to boost the skin's natural rejuvenation by over 50%.<1>
Restored Vitality & Luminosity
Clinically proven to improve the look of skin luminosity and vitality in 7 days.<2>
Refined Tone & Texture
Supports visibly smoother skin with improved tone and texture.
Visibly Calm, Resilient-Looking Skin
Clinically proven to improve skin barrier function in 7 days.<2>
Optimal Skin Recovery Support
Designed to support the skin's natural recovery processes, making it ideal for daily use and alongside professional treatments.
KEY INGREDIENTS
Prismatic PDRN
A pioneering form of vegan PDRN with a stable tetrahedral structure for optimal penetration. Composed of DNA particles that support skin recovery, help calm visible redness and reveal smoother, more youthful-looking skin.
Triple Exosome Complex
Designed to support natural skin signalling processes, resilience and recovery, helping to strengthen the skin barrier and promote a healthier, more radiant-looking complexion.
GF MiniProteinTM
Visibly improves the appearance of skin structure over time by helping to boost skin's collagen, elastin & hyaluronic acid levels.
ATP Precursor
An energy-carrying molecule that helps optimise the natural processes involved in visible skin rejuvenation.
HOW TO USE
After cleansing in the morning and evening, apply 1-2 pumps of Exo-PDRN Prismatic+ evenly across the face, neck & décolletage. Use light upward strokes and allow to fully absorb.
GOOD TO KNOW
CLINICALLY PROVEN
FRAGRANCE-FREE
DERMATOLOGICALLY TESTED
PROVEN GENTLE FORMULA
CERTIFIED BY THE VEGAN SOCIETY
Directions
After cleansing in the morning and evening, apply 1-2 pumps of Exo-PDRN Prismatic+ evenly across the face, neck & décolletage. Use light upward strokes and allow to fully absorb.
Test results
+50% boost in natural skin rejuvenation<1>7 days to improved skin barrier function<2>
7 days to improved skin luminosity<2>
7 days to visibly improved skin volume<2>
7 days to improved skin tone<2>
14 days to visibly improved wrinkles<2>
14 days to improved firmness<2>
100% agree this is the perfect post-procedure partner for their in-clinic PDRN treatment<3>
98% agree the results continue to get better with time<3>
<1> Proven via ex vivo study measuring Ki67 protein marker for cell proliferation vs. untreated control after 24 hours
<2> Proven via independent clinical study on Exo-PDRN Prismatic+ on 60 volunteers over 1 week
<3> Proven via independent consumer study conducted over 4 weeks on 52 participants who had received injectable polynucleotide treatments within a week of the study
Ingredients
Aqua (Water), Glycerin, Niacinamide, Lactobacillus Ferment, Centella Asiatica Leaf Extract, Lactobacillus Extracellular Vesicles, DNA, Punica Granatum Extract, Laminaria Digitata Extract, Oligopeptide-1, Disodium Adenosine Triphosphate, Sodium Hyaluronate, Lysine HCl, Proline, Histidine HCl, Arginine, Threonine, Serine, Valine, Alanine, Panthenol, Glutamic Acid, Leucine, Glycine, Taurine, Allantoin, Isoleucine, Phenylalanine, Polyacrylate Crosspolymer-6, Magnesium Aspartate, Butylene Glycol, Citric Acid, Calcium Pantothenate, Ethylhexylglycerin, 1,2-Hexanediol, Pentylene Glycol, Benzyl Alcohol, Caprylyl Glycol, Dehydroacetic Acid, Phenoxyethanol, Sodium Citrate.
This list of ingredients may be subject to change, please consult the packaging of the product purchased.
Free gift
FREE Advanced Night Restore 12.5ml, when you spend £85 on Medik8.*
*One free gift per order. Valid until 17th October or whilst stock lasts. Your free gift will automatically add to the shopping bag page. Total at order summary must be £85 or more worth of Medik8 products, after any Promotion Code, Brands You Love discount and before delivery charges are applied. Cannot be used in conjunction with any other Promotion and this offer is not applicable to previously made or pending purchases.
Excludes Gift Voucher, Sephora Favourites Advent Calendar and Fragrance Gift Box purchases. This offer is available online at Sephora.co.uk to UK Mainland customers only. Image used is for illustrational purposes only.
See more...
Rated 5 out of
5
by
Alison B. from
Verified buyer
[This review was collected as part of a promotion.] Fantastic product ,quickly absorbed,skin feels smooth and hydrated
Date published: 2026-10-10
Rated 5 out of
5
by
HUGUETTE D. from
I have seen a difference
[This review was collected as part of a promotion.] I have seen a difference in the texture of my skin it feels tighter. Have not seen any difference in my deep wrinkles yet!
Date published: 2026-10-10
Rated 5 out of
5
by
Christine J. from
Amazing stuff
[This review was collected as part of a promotion.] This has made such a difference to my skin. It has helped smooth some texture and is definitely helping with those wrinkles. I have now purchased a full size. It's a keeper in the routine.
Date published: 2026-10-10
Rated 5 out of
5
by
Emily S. from
Unbelievable
[This review was collected as part of a promotion.] I combine this, the peptides black bottle serum and the crystal retinal and I'm honestly so impressed with the results. Repeat purchase. Frown lines and fine lines are faded , my face feels hydrated and I get compliments on my skins complexion all the time.
Date published: 2026-10-08
Rated 5 out of
5
by
Anonymous from
Too soon to tell yet
[This review was collected as part of a promotion.] I had heard so much about this product hitting the beauty market
Trusting your brand I’m now on my second bottle. Easy to use and lightweight
I hope it’s a great one
Date published: 2026-10-08
Rated 5 out of
5
by
Tracy H. from
Exo PDRN prismatic
[This review was collected as part of a promotion.] It’s easily absorbed and gave my skin a brilliant boost leaving it super hydrated, it layers easily under my moisturiser.
Date published: 2026-10-07
Rated 3 out of
5
by
Imran L. from
not visible difference so far
Not seen much difference yet..but product texture is great
Date published: 2026-10-07
Rated 5 out of
5
by
ANNA F. from
Really pleased with the sample
[This review was collected as part of a promotion.] I really enjoyed trying this sample. It left my skin feeling soft, hydrated and refreshed, and I noticed a lovely healthy glow afterwards. I’d definitely be interested in trying the full size.
Date published: 2026-10-06
Help & Information
About
More From Sephora
Country Settings
United Kingdom- 4.2★★★★★
Download the Sephora App
